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What is Argireline?

what is argirelineArgireline is non-toxic, and affects the level of neuromuscular synapses, and causes muscle relaxation, preventing the formation of wrinkles. It also suppresses the overproduction of catecholamines (stress hormones) that promote the cause of wrinkles and small facial creases. It has been shown to suppress this so-called SNARE complex and catecholamine release. Here, we look at exactly what is Argireline, how it works, and what its are benefits.

Argireline Products help solve Anti-Aging Problems

Argireline reduces the appearance of stretch marks, thanks to the unique plumping technology involved. With this, the skin becomes firmer, more supple, and younger. Wrinkles are noticeably reduced and evenly smoothed out after even the first use. With regular use, this ingredient will reduce the wrinkles of the face, and small wrinkles will eventually disappear.  Deeper ones become more unnoticeable, thus preventing the appearance of new wrinkles. It is easily applied to wrinkles on the forehead, between the eyebrows, the “duck leg” and the so-called “barcode” lines of the lips.

In studies of facial products, wrinkles were 30% less in people whose skin was treated with a cream containing acetyl hexapeptide-3 every day for 1 month. It is worth noting that using a similar cream will not produce the same results as Botox injection, which is directly in the muscle. But, a product containing hexapeptide will prolong the positive effect of Botox. The benefits of cosmetic products with these ingredients are numerous. Best of all there is no pain or discomfort as with surgery or injections.

Face Cream containing Argireline versus Botox Injections

For the past 3-4 years, face creams containing this peptide have been offered as a local muscle relaxant. Some skincare products have difficulty reaching deep enough to have an effect on muscles and nerves. But, tests have proven that hexapeptides have the ability to act similarly to Botox injections by interacting with the neuro-chemical signal between the nerves and the muscles.

Argireline’s natural biopeptide is the perfect natural alternative to Botox. Cosmetics with this unique peptide are for people who want to remove the signs of aging skin but not lose the maximum expressiveness of their faces. This peptide has incredible healing capabilities for dying cells and tissue. It gives the cells longevity and vitality with excellent antioxidant, moisturizing and restorative properties.

Research Chemicals Study – Argireline (Acetyl hexapeptide-3)

Argireline or Acetyl hexapeptide-3 is a scientific discovery made in the process of studying the biochemical mechanisms that prevent aging. This substance is obtained through two modern technologies: combinatorial chemistry and solid-phase peptide synthesis. Argireline is a synthetic polypeptide similar to botulinum toxin or botox, but in contrast, it is safe to use and has no side effects. It is used in high-end cosmetics as an ingredient that visibly reduces the depth of wrinkles by paralyzing mimic muscles, the mechanism of action being analogous to Botox.

With its pronounced antioxidant properties, it prevents skin aging and the appearance of new wrinkles caused by repetitive facial movements. Cosmetic products containing Argilerine are mainly used to treat the areas around the eyes and forehead where the wrinkles appear. It is part of the make-up of creams and serums for the face. It is recommended that such cosmetics be used after the age of 40.

Botox effect of peptides (hexapeptides)

Depending on the length of the chain they form, the functions of the peptides differ. Tetrapeptides, for example, improve the condition of the delicate area around the eyes. Hexapeptides act on so-called dynamic wrinkles, gently relaxing the muscles. Such is the Acetyl Hexapeptide-3 (Argireline), a compound of six natural amino acids with a result close to that of Botox. After application to the skin, it penetrates the base layer of the epidermis, the nerve endings, where it modulates muscle contractions. It is used in anti-aging cosmetics. For more about these peptides read this article here: https://en.wikipedia.org/wiki/Acetyl_hexapeptide-3

Argireline extract

Peptides used in skincare are those that interact with skin cells and make them work in a certain way. They work by producing more collagen or thickening the skin layer. These peptides are able to enter the skin cells synthetically and remain whole. Therefore, the possibility of future development of new peptides is very promising. Studies have shown that tetra- and pentapeptides act as a chemical messenger in the body. This means they have the ability to increase the production of collagen A by the skin. Protein is essential in maintaining a good complexion and tight skin.

There are four important peptides in skincare: Acetyl Hexapeptide (Argireline), Palmitoyl Pentapeptide, Oligopeptide, and Copper Peptide

Peptides act in 3 different ways to improve the properties of the epidermis, reduce wrinkles, and finally give the skin a youthful look.

With aging, the collagen is destroyed without regeneration, resulting in wrinkles and dehydration. By treating skin with the peptides, it reminds the body that its own peptides have disappeared or decreased, and it must increase its peptides to regenerate collagen. Due to their low molecular weight, the peptides pass relatively easily through the main protective membrane of the epidermis, or the keratin layer. From the moment copper ions have attached to the surface, they are transferred to the deep layers of the epidermis. This then causes increased collagen production, and also provide excellent antioxidant and healing properties. These are absolutely essential for skin regeneration

Some peptides may block signal transduction. The major peptide in this category is Argireline-Neuropeptide, which works similarly to Botox and its proven results.

Advantages of Peptides:

 

·        Increase collagen production

·        Helps regulate the breakdown of collagen

·        Contributes to antioxidant enzymes

·        Improves cell recovery

·        Evens out the pigmentation

·        Offers protection against germs

The fact that there is a substance out there that can avoid premature aging is amazing! With so many people these days trying to stay younger looking, this is a tremendous step forward in the cosmetic industry. It is amazing now that this ingredient can be found easily in creams and lotions makes it assessable to all. Now you know the facts and what is Argireline, why not go and check it out for yourself?

 

 

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AICAR Capsules/Pills – A Future Miracle

AICAR CapsulesRecent news has suggested that researchers are in the process of developing a miracle pill, which provides all the benefits of exercise in one tablet! AICAR capsules or tablets might be a miracle soon and be able to turn couch potatoes into elite athletes. Sounds too good to be true, doesn’t it? Why not read on…

Scientists at the Salk Institute in La Jolla, California may have invented a miracle pill; containing the drug AICAR (aminoimidazole-carboxamide-ribonucleoside). The researchers have discovered that it works on humans as well as in experimental mice. It transforms inactive mice into athletes – without the animals having to train for it.

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The Peptide – AICAR Muscle Building Marvel

The physicians have been working on a 4-year-old research project, where they created genetically engineered mice with extreme endurance. In these so-called – marathon mice – the gene PPAR delta plays an essential role. The researchers then asked themselves whether medications could intervene in the PPAR delta-controlled metabolic cycles in order to give normal mice higher stamina. The researchers found that AICAR along with similar compound GW1516 were both successful substances interfering with muscle metabolism. For an in-depth read about this product see here: https://en.wikipedia.org/wiki/AICA_ribonucleotide

Research Peptides for Future Cures

Although GW1516 does not make as much progress from scratch, it dramatically increased real training, up to 70 percent more power than untreated mice on the treadmill with GW1516-fed animals.

So far, however, the study results only relate to endurance performance and not directly to muscle growth. Whether the preparations have any anabolic muscle building effect is not known. Of course, the abuse of this drug is likely for athletes in view that the impressive effect is very high. This is especially true in the run-up to the Olympic Games next year. The researchers are therefore already working with WADA on a doping test, which will also prove the use of AICAR and GW1516 retrospectively.

Where to Buy AICAR?

As of yet, the miracle exercise pill is still in clinical trials. But, there are research peptide companies that have AICAR capsules for sale. This peptide is also available in the injective form. These drugs are only sold for research purposes, but due to the muscle building characteristics, they are popular with bodybuilders.

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What is AICAR Used For?

AICAR, also known as Acadesine, is a research peptide originally developed as a drug for the treatment of cardiovascular diseases. It was initially used to enhance athletic performance in racehorses and other animals by stimulating the production of adenosine monophosphate-activated protein kinase (AMPK) in muscle tissues, which results in an increase in energy production and muscle endurance. However, AICAR has also shown potential benefits for medical use, such as promoting blood flow during heart surgery and as a treatment for diabetes.

Recent studies have found that AICAR can improve insulin sensitivity and glucose uptake in skeletal muscle, which may make it a useful treatment for type 2 diabetes. Additionally, AICAR has been investigated for its potential neuroprotective effects in the treatment of neurodegenerative diseases. It is important to note that research peptides like AICAR should only be used for research purposes. It is not for human consumption.

What is AICAR Used For?

Originally, AICAR was used to enhance athletic performance in horses and other animals by stimulating the production of adenosine monophosphate-activated protein kinase (AMPK) in muscle tissues. This results in an increase in energy production and muscle endurance.

However, AICAR has also shown potential benefits in medical research. For example, it has been investigated for its potential use in promoting blood flow during heart surgery, as well as its potential as a treatment for type 2 diabetes due to its ability to improve insulin sensitivity and glucose uptake in skeletal muscle. Additionally, AICAR has been studied for its potential neuroprotective effects in the treatment of neurodegenerative diseases.

Is AICAR a Steroid?

AICAR is not a steroid. It is a research peptide that has been developed for potential medical applications, specifically in the fields of cardiology and metabolic disorders. While AICAR has been investigated for its potential benefits in enhancing athletic performance, it is not classified as a steroid.

What is the Mechanism of AICAR?

The mechanism of AICAR, or Acadesine, involves activation of the AMP-activated protein kinase (AMPK) pathway. It is involved in regulating cellular energy metabolism. AICAR is converted inside the cell into an AMP analog, which activates AMPK and mimics the effects of energy depletion, leading to an increase in cellular energy production.

AMPK activation results in several downstream effects, including the stimulation of glucose uptake and fatty acid oxidation. At the same time as inhibiting energy-consuming processes such as protein and lipid synthesis.

AICAR has also been shown to stimulate the production of mitochondria, the cellular organelles responsible for energy production. These effects make AICAR a promising candidate for the treatment of metabolic disorders such as diabetes, as well as other conditions such as cardiovascular diseases and neurodegenerative diseases. It is important to note that research peptides like AICAR should only be used for research purposes and in compliance with all applicable laws, regulations, and ethical guidelines.

What Class of Drug is Acadesine?

Acadesine, also known as AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide). It is not classified as a drug, but rather a research peptide. AICAR is a synthetic nucleotide analog of adenosine that has been developed for potential medical applications, specifically in the fields of cardiology and metabolic disorders. It works by activating the AMP-activated protein kinase (AMPK) pathway, which is involved in regulating cellular energy metabolism.

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YK 11 Review – The Facts

If you are new to performance-enhancing drugs our YK11 review should help, so read on.  YK11 is a supplement that acts primarily as a myostatin inhibitor. It is designed to increase muscle mass, produce more healthy chemicals, and create healthy body growth that is sustainable for a longer period of time. There is some discussion as to whether or not it is a SARMs product. SARMs include Ostarine, Cardarine, Andarine, Ligandrol (LGD 4033) and Rad 140. While many classify it like this, others do not including YK 11.

What is YK 11?

It is important to know how YK11 works and what it does before using it. Some people feel that their effects are too strong and they do not want to change their bodies that way. However, those who love the benefits of increased muscle mass with a minimum of effort will love the YK11 experience and the way it improves their mass.

Before you read on, it is important to understand that this is not a steroid product. As a result, it will not seriously affect your testosterone levels. Therefore, you probably will not be dependent on this product. It has side effects when you use it and after you stop, but these results are usually not as rigorous as those of other muscle-building compounds.

YK11 Bodybuilding Miracle

YK11 is a myostatin inhibitor. Everyone has a genetic limit for building muscle. If we did not have a genetic wall in place, our body would continue to gain muscle mass, so, that it would not move physically because the mass would be so large.

Myostatin is responsible for this muscle-building wall. Men and women can exploit their genetic potential, and once they reach that point, Myostatin will engage even the best diet and training program. Myostatin inhibitors are able to disarm the substance and allow your body to develop further.

The YK 11 Experience

YK11 binds to an androgen receptor. This causes the muscle cells to produce more anabolic factors, which in turn leads to increased muscle growth. Unlike most SARMS, which have limited androgenic effects, this compound performs much better. An earlier study has shown that the effect of this compound on muscle cells is much higher. In this study, it was found that muscle cells produced more anabolic compounds when exposed to 500nmol of this compound than when exposed to testosterone.

Review of YK 11 Dangers

It’s safe to say that YK11 should help muscle growth. The compound has been shown to promote muscle growth, muscle retention, and new muscle cell growth. Its side effects are minimal and cannot be compared with the side effects of steroids available on the market. This may explain why it receives a lot of attention, as many are looking for a solution that is safe and promotes muscle growth.

This compound is great for those who want to build muscle mass. The compound is also ideal for people who want to maintain the amount and quality of their muscles and keep fat cells at bay.

Pros and Cons of YK 11

This compound was primarily developed to help with muscle growth. It works in more ways than one to promote the development of muscle cells and ensure muscle retention. The compound also works to help burn fat and reduce the total amount of fats that are deposited in the body.

When introduced into the body, YK11 ensures that muscle cells develop much faster. The compound also strengthens the existing muscle mass. Because the drug is selective, users can see the results much faster and get better results.

A cure for muscle wastage diseases

This compound is designed to help people whose genetic predisposition prevents them from building significant muscle mass. This is because it also represents a myostatin inhibitor. Myostatin is a protein that inhibits muscle growth in the body. Of course, some people have a high amount of this protein in their bodies. Such people rarely acquire significant muscle mass, even when using available muscle building solutions. Thanks to YK11, people who are naturally disadvantaged in terms of muscle growth can also bring their muscles to the desired level.

Additional YK 11 Benefits – Hair growth

This can be a positive or negative side effect. For users who also want to increase their hair growth, this is a welcome side effect. Some people can also be deterred by the increased hair growth. However, removing this excess hair is easy and it does not seem to be such a big deal, especially if you are experiencing significant muscle growth.

Some steroids are known to cause hair loss when used for some time. This compound is ideal for people who have experienced hair loss as a result of using steroids and are looking for a quick and effective solution to help them grow their hair back.

Effect on the prostate

It has been found that this compound does not cause any androgenic effects on the prostate. Unlike most steroids, which are also known to cause prostate enlargement, this compound has no effect on the prostate. Men can therefore use without having to worry about prostate enlargement and related problems.

YK-11 does not require a missing compound to be activated. Rather, it combines with an androgen receptor in the body and promotes the release of the compound follistatin. There are some side effects to discuss but nothing as severe as a prohormone. Prohormone and YK11 have completely different activation mechanisms, with anabolic and androgenic effects being different. In summary, YK-11 is NOT a prohormone.

Example – YK11 dosage and timing

Each person is different so it is basically impossible to say how much a YK 11 cycle contributes to the overall result. From a lot of research on forums with YK11 for sale, it is recommended between 10-30mg per day which can lead to lean muscle growth of between 8-12lbs over a period of several weeks. High doses over a longer period of time can potentially lead to higher gains, but it is a matter of starting low and increasing gradually.

Is YK 11 Legit?

YK-11 is fully legal in the United States, United Kingdom and worldwide, and there are no steps to ban its use. It is completely legal and affordable to buy online, unlike anabolic steroids, which are obviously illegal. YK 11 is classed as a research chemical and should not be used for human consumption. But, as you have discovered it is widely used among bodybuilders to build muscle. YK 11 is banned in all sporting competitions around the globe. If you want more scientific information about YK 11 read this link: https://www.ncbi.nlm.nih.gov/pubmed/23995658

Side effects

Concluding our YK 11 review it gives really good results and makes your muscles grow without much control. However, inhibition of myostatin can be dangerous as it can weaken your tendons and reduce your stamina. The verdict is that it is still in the early stages of study but if you want to experiment a little, a single cycle will not kill you.

People say that learning from your own experience is the best and in the case of YK 11 is probably right! We hope you have enjoyed this YK 11 review. If you are interested in buying YK 11 it is widely available. Just make certain you buy quality and from a reputable source.

 

 

 

 

 

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Effective LGD 4033 Capsules for Sustainable Muscle Building

LGD 4033 CapsulesLGD 4033 or Ligandrol is considered the strongest SARM for effective muscle growth. Ligandrol or LGD 4033 is not a member of the steroid family but instead is referred to as a selective androgen receptor modulator or SARM. This means it binds with the so-called androgen receptors of the bones and especially the skeletal muscle. Scientists have proven it has muscle-building benefits and can strengthen bones.  This means it is ideal for bodybuilding. LGD 4033 is effective as an alternative to a prohormone cycle. Research has shown that LGD-4033 can be far more effective than Ostarine. The SARM LGD 4033 capsules form an effective way to sustainably build muscle without disturbing or harmful side effects.

The Mode of Action of the SARM LGD-4033

LGD 4033 capsules when taken continuously over a period of time greatly enhance the anabolic effects of testosterone with a reduction in androgenic side effects. Therefore, problems or typical side effects of known steroids are unlikely. Functionally, LGD-4033 selectively binds the androgen receptors. The anabolic activity in the muscle and in the bones is significantly intensified without negatively influencing prostate growth. Anabolic steroids of the past, however, were known to increase side effects, in these areas!

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SARMs Capsules for Muscle Growth and Fat Reduction

LGD capsules reveal their strength especially in building muscle. They do not have to be used exclusively in bodybuilding. Even with a diet, the SARM can be used as an advantage, as it has good anti-catabolic protection. In bodybuilding LGD 4033 is very effective because SARMs of this kind have a strong anabolic component and the ability to specifically build lean muscle mass. At the same time, LGD-4033 reduces body fat, allowing it to be used both in bodybuilding to build up mass and within a diet. The SARMs capsules can also be used to increase the strength only. Thus, the capsules allow an explicit intensive training at any time. Those who use LGD 4033 for muscle building should concentrate on a high-protein diet. A correspondingly high intake of protein is of enormous importance for fat reduction.

For more information on this SARM read here:https://www.usada.org/spirit-of-sport/education/5-things-to-know-about-lgd-4033/

LGD 4033 Capsules Dosage Recommendation

Scientific studies have shown that in bodybuilding within three weeks the daily intake of only 1 mg of Ligandrol increased muscle build-up of about 1.5 kg of pure muscle mass. However, since dosages of up to 10 mg per day are taken in practice, the bodybuilding muscle buildup can be much more intense. Women, who do bodybuilding taking a daily dosage of 3 mg, have a clearly visible effect on muscle development. However, when taking capsules, women should always bear in mind that – in contrast to the example of Ostarine – residual androgen doses may be more noticeable. Researchers’ studies show that SARMs such as the LGD 4033 can be taken in combination with all other SARMs capsules. Suggested Dosage – Men should take two capsules daily of 5 mg per capsule each and women one capsule daily. The duration of the intake should be eight weeks.

PCT is Recommended for the SARM LGD 4033

It is important after a cycle of Sarms LGD 4033 capsules a post-cycle therapy (PCT) is recommended. Although anabolic steroids significantly suppress the body’s own hormone production, compared to other SARMs this suppression of LGD 4033 is still much stronger. These circumstances make a PCT a necessary phase.

At Glance Advantages of LGD-4033 Capsules

  • High gains in muscle mass and muscle strength
  • Studies have shown that there are only minimal side effects
  • LGD-4033 has medical benefits

A final note is, for a faster increase in muscle, some athletes stack LGD 4033 capsules with Ibutamoren or MK 677. Or for a faster way to lose fat stack LGD 4033 with GW 501516 or Cardarine. See our list of products available, also are alternatives to LGD 4033 capsules.