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What is Kisspeptin?
Kisspeptin is a protein that occurs naturally in the body. It plays a crucial role in signaling hormones during puberty and reproduction. Recent studies show it can change behavior and mood, promote regeneration, and normalize kidney function. The Kisspeptin peptide exists in the brain and can restrain the growth and spread of tumors.
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The peptide kisspeptin is an important discovery due to its ability to impact the gonadotropin-releasing hormone. Kisspeptins are a group of proteins that are connected with fertility. It was discovered in the mid-1990s in the USA.
How does Kisspeptin Work?
Kisspeptin works with the nerve endings of the GnRH neurons to regulate the release of GnRH secretion. It influences the gonadotropin-releasing hormone (GnRH). These hormones play an essential role in managing testosterone and a form of estrogen.
Studies with Kisspeptin Supplement
In temperate regions, the natural reproduction of goats and sheep is conditioned by the seasons, with births occurring in spring. Therefore, to achieve milk production throughout the year to meet consumer demand, it is necessary to apply hormonal treatments to obtain deliveries in the fall.
These hormonal treatments consist of the application of an analog to progesterone and ECG. However, these treatments may have reduced efficacy in the long term due to the animals’ immune response to ECG. Alternative methods to hormonal treatment include the male effect or changes in the photoperiod, but they do not fully satisfy the needs of producers.
The Solution – Neuropeptide Kisspeptin
Research on the reproductive cycle of small ruminants has revealed the role of the endogenous neuropeptide, Kisspeptin. Although this peptide has no direct application in animals, researchers from INRA and CNRS have developed a similar molecule used for reproductive purposes in small ruminants: kisspeptin C6.
The same research group has tested the effects of this synthetic peptide on FSH and LH levels and the reproductive capacity of animals.
The study results showed that C6 Kisspeptin can trigger ovulation, increasing the secretion of endogenous gonadotropins in any reproductive period, both during the fertile phases and in the anestrus.
The results of this study open a new strategic line for the reproductive control of animals, framed in a system that respects the environment and the health of animals.
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As with all research peptides, there is still more work to be done before it is allowed for use in mainstream medicine. Here we have looked at some of the varying studies performed so far with Kisspeptin. It appears to have many positive results in reproduction and more. To summarize Kisspeptin influences testosterone levels and sex-related behaviors, and libido, and further research has found it can treat signs of aging.
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