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Posted on Category:Capsules
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Tesofensine Where To Buy?

Tesofensine 500mcg (30 Capsules) is a research peptide. It is a serotonin-noradrenaline-dopamine reuptake inhibitor and was first tested for its effect on Parkinson’s and Alzheimer’s. But, studies found a side effect of tesofensine was dramatic weight loss and reduced appetite.

Thus, manufacturer of Tesofensine Capsules are currently testing the benefits of the reuptake inhibitors for the treatment of obesity and its associated conditions, type 2 diabetes and metabolic syndrome. One of the most promising results has been the potential to treat people with obesity. The research peptide Tesofensine is available only for research.

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Tesofensine Capsules – Important Facts

This product is currently being researched and is not a known medical product. The manufacturer are currently conducting clinical trials on the potential of this medication in the treatment of obesity and its associated conditions, type 2 diabetes and metabolic syndrome.

The manufacturer of Tesofensine are currently conducting clinical trials on the potential of this medication in the treatment of obesity and its associated conditions, type 2 diabetes and metabolic syndrome.

Tesofensine Ingredients

Tesofensine is manufactured by Saniona since 2014. It is being studied for the treatment of people with the symptoms of type 2 diabetes and metabolic syndrome.

How Does Tesofensine Work?

Tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor. It stops serotonin, noradrenaline and dopamine from being taken back into the cells.  It was first tested for its effect on people with Parkinson’s and Alzheimer’s. Tesofensine works by reabsorption, where it works in a similar way to a neurotransmitter. Tesofensine increases the concentration of dopamine, noradrenaline and serotonin. The result of increased neurotransmitter concentration is increased satiety, decreased eating or increased energy.

Side effects Of Tesofensine

As with all drugs, Tesofensine has side effects. The most common side effects include loss of appetite, anxiety, sleep disturbance, nausea and increased vomiting. If you have heart problems, speak to your doctor before taking Tesofensine.

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Tesofensine is a potentially new weight loss medication currently undergoing clinical trials. Research suggests Tesofensine is more effective than Xenical and Reductil. These are the two slimming pills currently on the market. European trials report that patients who were dieting and took the highest amount of the medication for six months lost up to 12% of their body weight.

Tesofensine peptide is the latest drug testing for the treatment of obesity. In chemical terms, it is a Serotonin Noradrenaline, Dopamine Phenyltropane Reuptake Inhibitor. It is a weight loss agent that suppresses hunger and increases the feeling of a full stomach. A process due to the reuptake of substances responsible for hunger, such as serotonin, norepinephrine and dopamine. At the present time it should be taken under medical advice and follow the specialist’s instructions.

How Tesofensine Is used?

The research consists of giving patients 0.5 mg of tesofensine daily and a calorie-restricted diet.

Tesofensine Side Effects

Side effects of tesofensine are dry mouth, nausea, insomnia, diarrhoea, irritability, increased sweating, tremors, decreased libido, and increased blood pressure.


Tesofensine is a research peptide. It is still in the early stages of study. It is contraindicated in people with high blood pressure, pregnant or lactating women and children.

Tesofensine Reviews

Tesofensine is a research peptide that shows promising results for combatting obesity. It works by inhibiting the reuptake of certain neurotransmitters, including serotonin, norepinephrine, and dopamine, leading to increased feelings of fullness and reduced appetite.
Clinical trials conducted up to that point had shown promising results regarding weight loss and improvements in metabolic parameters. Some research suggested that Tesofensine might be more effective than existing weight loss medications.

Tesofensine 500mcg (30 Capsules) is a research peptide formulation, with each capsule containing 500mcg of Tesofensine. This intriguing compound operates as a serotonin-noradrenaline-dopamine reuptake inhibitor, and its origins trace back to initial investigations into its potential impact on neurological conditions like Parkinson’s and Alzheimer’s disease. However, during these studies, an unexpected side effect emerged: significant weight loss and a marked reduction in appetite. Consequently, Tesofensine has garnered substantial attention in the realm of research for its potential benefits in weight loss.

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Posted on Category:Capsules

Tesofensine 500mcg (30 Capsules)

Tesofensine is a drug in development for the treatment of obesity and weight loss. Initially, it was tested as a drug to treat Alzheimer’s and Parkinson’s disease, and although it did not show significant results in these diseases, it had a weight loss effect in patients who received the experimental treatment. Tesofensine has very effective weight loss properties, and is considered a possible drug to treat obesity.

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The products on our website are intended for research purposes only and not for the use on the human body

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How Does Tesofensine Work?

Like many human diseases, obesity is a disease that starts in the brain, and that’s exactly where tesofensine works to decrease appetite. After the negative results of the drug for the treatment of Parkinson’s and Alzheimer’s, more studies were carried out to study whether tesofensine makes you lose weight. As a result of these studies, it has been proven that tesofensine can be a good drug for weight loss and fighting obesity.

Tesofensine is considered a presynaptic drug that inhibits dopamine, serotonin and noradrenaline. When these neurotransmitters are not reabsorbed by the central nervous system, the body’s response is to feel less hungry. Thus, patients eat less. Tesofensine also appears to be able to affect the feeling of pleasure involved with eating by modulating the action of dopamine in a specific sector of the brain.

How Does Tesofensine Work?

In a clinical study of 203 people (half of them taking a placebo), those taking a placebo had a 2% body weight loss, while those taking tesofensine had a much greater loss. Patients taking a 0.25 mg tesofensine experienced a 6.5% weight loss; patients taking the intermediate 0.5 mg of the drug lost 11.2% of their body weight; and those taking the highest 1 mg lost 12.6% of their body weight. In the higher groups, there was a four-point drop in BMI over a 24-month period.

Other benefits that patients experienced by taking tesofensine were:

  • reduced appetite after 14 days of taking the drug, plus a better feeling of fullness and less desire to eat;
  • increased fat oxidation and decreased adipose tissue. Fat oxidation increased by 15% and protein oxidation was lower. Tests have proven the decrease in adipose tissue;
  • higher levels of insulin sensitivity have been noted, increasing and improving glucose metabolism, making it a good drug for patients at risk for type 2 diabetes;
  • increase in energy expenditure by 6% after 14 days of drug use, directly linked to the use of tesofensine. 

Is Research Peptide Tesofensine Safe?

Unfortunately, even during the study, tesofensine showed some side effects: increased heart rate (abnormally fast pulse), high blood pressure, and muscle wasting. Any weight loss medication should focus on eliminating fat tissue while leaving lean muscle mass intact. This does not appear to be the case with tesofensine, which also caused muscle wasting.

For the same reasons, it was decided at the end of the study that further clinical trials of tesofensine were needed before it could be produced and marketed as a drug for the treatment of obesity, as it had demonstrated possible harmful effects.

In 2011, the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) gave their opinions on the development of tesofensine. The next phase of the study could take three to five years or more.

Final Considerations 

Tesofensine is an effective research peptide to help obese people lose weight. Studies show its effects work to cause real and significant weight loss. For some patients, a drug like tesofensine can be the difference between losing weight “naturally” and losing weight with surgery, such as bariatric (stomach reduction).

According to the results of studies, it is possible to see that there is still no drug to treat obesity that is free of side effects, and that if tesofensine reaches the market, which may still take many years to happen, it will not be a medicine that can be used by all people.

It is also worth remembering that tesofensine is a drug that will be sold under medical prescription and that, when marketed, will be used in the treatment of obesity. In the case of overweight or just a few extra pounds, the best solution to lose weight remains a healthy and balanced diet and regular exercise, generating a slow and lasting weight loss.

About Research Peptide Tesofensine Capsules

Research peptide Tesofensine is a promising compound in the field of longevity research. It primarily acts by blocking the activity of the enzyme nicotinamide N-methyltransferase (NNMT), which increases NAD+ levels. NAD+ is a crucial cofactor central to cellular metabolism and declines with age. By elevating NAD+ levels, Tesofensine enhances metabolic rate and activates the “longevity gene” SIRT1. SIRT1 plays a crucial role in reducing the risk of various age-related diseases, including diabetes, obesity, metabolic syndrome, cardiovascular diseases, kidney diseases, liver diseases, neurodegenerative conditions, and cancer.

Moreover, Tesofensine’s effects extend to cellular aging, where increased levels of NAD+ support the survival and proliferation of healthy cells, thereby improving tissue function and mitigating the effects of aging.

Notably, Tesofensine is for research purposes only. It should be handled by licensed professionals in laboratory settings only.

The Need For Research Tesofensine To Help Obesity

Finding a cure for weight gain and obesity is paramount in our modern society. Obesity is not merely a cosmetic concern; it is a complex, chronic medical condition associated with many serious health risks, including:

  • diabetes,
  • heart disease
  • certain cancers
  • mental health issues.

It places an immense burden on healthcare systems worldwide, escalating healthcare costs. Beyond the health implications, obesity can significantly diminish one’s quality of life, limiting mobility and leading to physical and emotional challenges.

Moreover, the societal impact is substantial, affecting individuals across age groups, ethnicities, and socioeconomic backgrounds. Therefore, pursuing effective treatments and preventive measures is essential. Its not just a matter of personal well-being but far-reaching implications for public health, healthcare sustainability, and overall societal well-being.


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Moreover, a reputable company like Peptide Sciences strongly emphasizes compliance with ethical and legal regulations, ensuring the safety and well-being of both researchers and the wider community. Choosing our trusted partner, Peptide Sciences to buy Tesofensine will make all the difference in pursuing groundbreaking discoveries and advancements in scientific research.